Bronchoconstriction following instillation of phenylephrine eye drops in premature infants with bronchopulmonary dysplasia: two cases report
نویسندگان
چکیده
Premature infants requiring an ophthalmic examination or even surgery for retinopathy of prematurity (ROP) have a high prevalence of co-existing bronchopulmonary dysplasia (BPD). Reactive airway is one of the clinical presentations of BPD. We report two cases of bronchoconstriction following instillation of mydriatic eye drops. One occurred during induction of anesthesia for laser photocoagulation and the other before screening of ROP. The most likely cause in each case was phenylephrine eye drops. We recommend that the minimal dosage of phenylephrine needed to attain proper mydriasis should be instilled to infant patients, and the possibility of bronchoconstriction occurrence kept in mind, especially for infants with low body weight with BPD.
منابع مشابه
The pain response to mydrin-P eye drops in premature neonates
Background: To evaluate the pain responses of premature neonates after the instillation of mydriatic eye drops (Mydrin-P; 0.5% tropicamide and 0.5% phenylephrine hydrochloride) for retinal examination. Methods: Fifty premature infants (100 eyes) of birth weight (≤ 1501 g) or gestational age (≤ 32 w) who underwent Retinopathy of Prematurity (ROP) examinations between December 2014 and June 2015 ...
متن کاملRelationship between Ureaplasma urealyticum Colonization and Bronchopulmonary Dysplasia in Very Low Birth Weight Premature Infants: A Prospective Cohort Study
Background: Bronchopulmonary dysplasia (BPD) is the second prevalent lung disease and one of the care challenges of premature newborns. Different risk factors play an important role in the development of this disease. Therefore, the aim of the present study was to investigate the relationship between colonization with Ureaplasma urealyticum and BPD.Methods: This prospective cohort study w...
متن کاملA mydriatic eye-drop combination without systemic effects for premature infants: a prospective double-blind study.
Eye drops used for diagnostic mydriasis may produce systemic side effects in preterm infants. Studies on the pupil dilating and systemic effect of various mydriatic agents yielded conflicting results. We conducted a prospective randomized double-blind study on the systemic effect of two mydriatic eye-drop combinations. Thirty-nine preterm infants were randomly assigned to two groups. An eye-dro...
متن کاملLower conjunctival fornix packing for mydriasis in premature infants: a randomized trial
OBJECTIVE To compare the mydriatic effect of lower conjunctival fornix packing to conventional instillation of eyedrops containing 2.5% phenylephrine and 1% tropicamide in premature infants undergoing examination for retinopathy of prematurity. METHODS The patients were randomized to receive either conventional instillation of mydriatic drops or lower conjunctival fornix packing in one eye an...
متن کاملAirway administration of corticosteroids for prevention of bronchopulmonary dysplasia in premature infants: a meta-analysis with trial sequential analysis
BACKGROUND Uncertainly prevails with regard to the use of inhalation or instillation steroids to prevent bronchopulmonary dysplasia in preterm infants. The meta-analysis with sequential analysis was designed to evaluate the efficacy and safety of airway administration (inhalation or instillation) of corticosteroids for preventing bronchopulmonary dysplasia (BPD) in premature infants. METHODS ...
متن کامل